Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | PPARD | Q03181 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764690 | 1.00 | PPARG (0.64) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL25195919 | 1.00 | PPARG (0.64) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL13764688 | 0.89 | PPARG (0.50) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL30384025 | 0.88 | PPARG (0.65) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL30383987 | 0.88 | PPARG (0.65) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL4471370 | 0.88 | PPARG (0.65) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL13817902 | 0.88 | PPARG (0.65) | PPARGPPARDPPARAMAPTLMNA | |
| SCHEMBL30384453 | 0.87 | CXCL12 (0.52) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL13764683 | 0.87 | CXCL12 (0.52) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL25203939 | 0.87 | CXCL12 (0.52) | PPARGPPARDPPARAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |