Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17670333 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL30384722 | 0.93 | LRRK2 (0.39) | SMN1; SMN2MAPTALDH1A1LRRK2DCLK1 | |
| SCHEMBL17670207 | 0.93 | LRRK2 (0.39) | SMN1; SMN2MAPTALDH1A1LRRK2DCLK1 | |
| SCHEMBL17670158 | 0.93 | PTK2 (0.39) | MAPTALDH1A1LRRK2MAPK7ALK | |
| SCHEMBL30384375 | 0.88 | GAA (0.41) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL17670245 | 0.88 | GAA (0.41) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL30384778 | 0.87 | EGFR (0.39) | SMN1; SMN2NPC1RAB9AGAALRRK2 | |
| SCHEMBL17670221 | 0.87 | EGFR (0.39) | SMN1; SMN2NPC1RAB9AGAALRRK2 | |
| SCHEMBL17670453 | 0.83 | EGFR (0.37) | MAPTALDH1A1LMNALRRK2ALK | |
| SCHEMBL17670459 | 0.83 | EGFR (0.42) | MAPTALDH1A1LRRK2ALKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111686110-B | Compounds and compositions for modulating EGFR mutant kinase activity | 株式会社柳韩洋行 | 2023-06-16 | — | — | CN | disclosed |