Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 1.00 |
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.85 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | FLT3 | P36888 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30384240 | 1.00 | MAOB (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL25223438 | 1.00 | MAOB (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL634191 | 1.00 | MAOB (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL634190 | 1.00 | MAOB (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL25188874 | 0.92 | MAOB (0.85) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL3396591 | 0.92 | PTGS1 (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL29427953 | 0.92 | PTGS1 (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL25195740 | 0.92 | PTGS1 (1.00) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL25265209 | 0.92 | MAOB (0.85) | MAOBABCG2ACHEPTGS1PTGS2 | |
| SCHEMBL3396596 | 0.92 | PTGS1 (1.00) | MAOBABCG2ACHEPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |