Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TTK | P33981 | 3/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.32 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30386226 | 0.99 | TP53 (0.33) | TP53LMNATTKPTK2JAK2 | |
| Iodide SCHEMBL25170266 | 0.92 | PTK2 (0.34) | TTKPTK2PTK6 | |
| Iodide SCHEMBL25170264 | 0.92 | PTK2 (0.34) | TTKPTK2PTK6 | |
| Iodide SCHEMBL30385508 | 0.92 | TTK (0.32) | TTKPTK2JAK2JAK3JAK1 | |
| Iodide SCHEMBL30386062 | 0.91 | TP53 (0.35) | TP53LMNATTKPTK2JAK2 | |
| SCHEMBL25173474 | 0.91 | TTK (0.35) | TP53LMNATTKPTK2PTK6 | |
| Iodide SCHEMBL30386017 | 0.90 | TTK (0.35) | TTKPTK2PTK6 | |
| SCHEMBL30385437 | 0.90 | TP53 (0.40) | TP53LMNAPTK2JAK2JAK3 | |
| SCHEMBL30385499 | 0.90 | TP53 (0.38) | TP53LMNATTKPTK2JAK2 | |
| SCHEMBL25173554 | 0.90 | PTK2 (0.35) | TTKPTK2PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |