Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385873 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29020762 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30384666 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29169381 | 0.87 | MEN1 (0.58) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL25738505 | 0.87 | MAPT (0.60) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30385538 | 0.87 | MAPT (0.60) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085201 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085189 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30604697 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085169 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919859-B | Pharmaceutical composition of heteroaryl derivative and application of pharmaceutical composition in medicine | 四川海思科制药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-115919859-A | Pharmaceutical composition of heteroaryl derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-07 | — | — | CN | disclosed |