Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.39 |
| ▸ | LCK | P06239 | 6/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | TTK | P33981 | 2/20 | 0.34 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122917 | 1.00 | PTK6 (0.45) | PTK6AURKBLCKJAK2JAK1 | |
| Trifluoroacetic Acid SCHEMBL30172047 | 0.96 | PTK6 (0.43) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22142746 | 0.93 | PTK6 (0.47) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL28982245 | 0.90 | JAK1 (0.37) | PTK6JAK2JAK1 | |
| SCHEMBL25450862 | 0.90 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL32675698 | 0.90 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25450905 | 0.90 | PTK6 (0.36) | PTK6AURKBLCKTTK | |
| SCHEMBL32675687 | 0.90 | PTK6 (0.36) | PTK6AURKBLCKTTK | |
| SCHEMBL22142817 | 0.89 | PTK6 (0.44) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL22139163 | 0.89 | PTK6 (0.44) | PTK6AURKBLCKTTKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |