Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555832 | 0.89 | DPP4 (0.82) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556300 | 0.84 | DPP4 (0.49) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3035783 | 0.83 | DPP4 (0.69) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL556572 | 0.82 | DPP4 (0.72) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL27583022 | 0.82 | DPP4 (0.79) | DPP4ALDH1A1SMN1; SMN2CHRM1CHRM2 | |
| SCHEMBL3002431 | 0.80 | DPP4 (0.64) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL556617 | 0.80 | DPP4 (0.82) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555566 | 0.80 | DPP4 (0.82) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555204 | 0.80 | DPP4 (0.72) | DPP4KMT2AALDH1A1MEN1CHRM1 | |
| SCHEMBL555414 | 0.80 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204250-A1 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA & CO. KG (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204250-A1 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP3, DPP7 | DPP4 1/4885KMT2A 3475/4885ALDH1A1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.