Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 9/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112110 | 1.00 | TTK (0.37) | TTKPTK2PTK6PDE4BPDE4D | |
| Iodide SCHEMBL25170442 | 0.99 | TTK (0.37) | TTKPTK2PTK6PDE4BPDE4D | |
| Iodide SCHEMBL25170443 | 0.99 | TTK (0.37) | TTKPTK2PTK6PDE4BPDE4D | |
| Trifluoroacetic Acid SCHEMBL30385277 | 0.96 | TTK (0.35) | TTKPTK2PTK6PDE4BPDE4D | |
| SCHEMBL25173474 | 0.93 | TTK (0.35) | TTKPTK2PTK6CNR2MAP3K7 | |
| SCHEMBL24112510 | 0.92 | PTK2 (0.37) | TTKPTK2PTK6RETCNR2 | |
| SCHEMBL25173554 | 0.92 | PTK2 (0.35) | TTKPTK2PTK6RETCNR2 | |
| Iodide SCHEMBL30386017 | 0.92 | TTK (0.35) | TTKPTK2PTK6RETCNR2 | |
| Iodide SCHEMBL25170264 | 0.92 | PTK2 (0.34) | TTKPTK2PTK6PDE4BPDE4D | |
| Iodide SCHEMBL25170266 | 0.92 | PTK2 (0.34) | TTKPTK2PTK6PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |