Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385583 | 0.95 | MDM2 (0.48) | KMT2AMDM2MDM4TP53CASP3 | |
| SCHEMBL30403561 | 0.95 | MDM2 (0.48) | KMT2AMDM2MDM4TP53CASP3 | |
| SCHEMBL28982176 | 0.95 | MDM2 (0.48) | KMT2AMDM2MDM4TP53CASP3 | |
| SCHEMBL28982175 | 0.95 | MDM2 (0.48) | KMT2AMDM2MDM4TP53CASP3 | |
| SCHEMBL30385972 | 0.91 | MDM2 (0.45) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL5631124 | 0.91 | KMT2A (0.47) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL5631131 | 0.91 | KMT2A (0.47) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL31655377 | 0.88 | KMT2A (0.53) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL5566356 | 0.88 | KMT2A (0.53) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL30229675 | 0.88 | KMT2A (0.53) | KMT2AMDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |