SCHEMBL30385927

SCHEMBL30385927

COCCNc1cc(NC(=O)c2cn(C)c3ccc(C=O)nc23)ncc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25187791 1.00 FGFR4 (1.00) FGFR4
SCHEMBL25189852 0.89 FGFR4 (1.00) FGFR4
SCHEMBL30385803 0.89 FGFR4 (1.00) FGFR4
SCHEMBL30385738 0.88 FGFR4 (1.00) FGFR4
SCHEMBL25190748 0.88 FGFR4 (1.00) FGFR4
SCHEMBL25193283 0.84 FGFR4 (1.00) FGFR4
SCHEMBL30385596 0.84 FGFR4 (1.00) FGFR4
SCHEMBL25191058 0.81 FGFR4 (1.00) FGFR4
SCHEMBL30385924 0.81 FGFR4 (1.00) FGFR4
SCHEMBL25190401 0.80 FGFR4 (1.00) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO claimed
CN-116102549-A 5-aldehyde heterocyclic amide compound and application thereof 暨南大学 2023-05-12 — — CN claimed
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO disclosed
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