Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 12/20 | 0.37 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25176438 | 0.88 | PTK6 (0.47) | PTK6TTKMAPKAPK5 | |
| SCHEMBL24977795 | 0.85 | TTK (0.37) | PTK6TTKMAPKAPK5 | |
| SCHEMBL24105244 | 0.81 | TTK (0.42) | PTK6TTKMAPKAPK5 | |
| SCHEMBL30167898 | 0.81 | TTK (0.42) | PTK6TTKMAPKAPK5 | |
| SCHEMBL22124594 | 0.79 | PTK6 (0.48) | PTK6TTKMAPKAPK5 | |
| SCHEMBL22124129 | 0.79 | PTK6 (0.47) | PTK6TTKMAPKAPK5 | |
| SCHEMBL22124200 | 0.79 | PTK6 (0.47) | PTK6TTKMAPKAPK5 | |
| SCHEMBL30171998 | 0.79 | PTK6 (0.47) | PTK6TTKMAPKAPK5 | |
| SCHEMBL22123950 | 0.78 | PTK6 (0.49) | PTK6TTKMAPKAPK5 | |
| SCHEMBL22142737 | 0.78 | PTK6 (0.50) | PTK6TTKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |