Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.45 |
| ▸ | TTK | P33981 | 5/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123546 | 1.00 | MAPKAPK5 (0.47) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL22124321 | 0.93 | MAPKAPK5 (0.47) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL30384851 | 0.93 | MAPKAPK5 (0.47) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL30385742 | 0.91 | MAPKAPK5 (0.48) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL25170256 | 0.91 | MAPKAPK5 (0.48) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL22123619 | 0.90 | PTK6 (0.54) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL30193410 | 0.90 | PTK6 (0.54) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL25170375 | 0.86 | PTK6 (0.40) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL24112103 | 0.86 | PTK6 (0.49) | MAPKAPK5SYKPTK6TTKAURKB | |
| SCHEMBL30349725 | 0.85 | MAPKAPK5 (0.55) | MAPKAPK5SYKPTK6TTKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |