Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.80 |
| ▸ | EED | O75530 | 3/20 | 0.80 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.80 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.80 |
| ▸ | RBBP7 | Q16576 | 3/20 | 0.80 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.51 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12684066 | 1.00 | EZH2 (0.80) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684224 | 0.96 | EZH2 (0.78) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684323 | 0.95 | EZH2 (0.77) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL15490771 | 0.94 | EZH2 (0.80) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL15490775 | 0.93 | EZH2 (0.83) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684183 | 0.92 | EZH2 (0.81) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684051 | 0.92 | EZH2 (0.89) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684381 | 0.91 | EZH2 (0.79) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684468 | 0.90 | EZH2 (0.86) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12499687 | 0.90 | EZH2 (1.00) | EZH2EEDRBBP4SUZ12RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2023-05-10 | — | — | EP | disclosed |