Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 0.68 |
| ▸ | EED | O75530 | 3/20 | 0.58 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.58 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.58 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.58 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.51 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498940 | 1.00 | EZH2 (0.68) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12498804 | 0.92 | EZH2 (0.67) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL30387685 | 0.92 | EZH2 (0.67) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12499131 | 0.90 | EZH2 (0.65) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL30387736 | 0.89 | EZH2 (0.72) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12499156 | 0.89 | EZH2 (0.72) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12180676 | 0.88 | EZH2 (0.71) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12499671 | 0.88 | EZH2 (0.65) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12498209 | 0.88 | EZH2 (0.67) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL30388002 | 0.88 | EZH2 (0.65) | EZH2EEDRBBP4SUZ12RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2023-05-10 | — | — | EP | disclosed |