Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.57 |
| ▸ | CNR1 | P21554 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044068 | 0.77 | CNR2 (0.69) | CNR2CNR1MAPK1TSHRPKM | |
| SCHEMBL3044139 | 0.72 | CNR2 (1.00) | CNR2CNR1MAPK1TSHR | |
| SCHEMBL3044583 | 0.71 | CNR2 (1.00) | CNR2CNR1MAPK1TSHRPKM | |
| SCHEMBL3040656 | 0.69 | CNR2 (1.00) | CNR2CNR1HTT | |
| SCHEMBL3030369 | 0.69 | CNR2 (1.00) | CNR2CNR1MAPK1 | |
| SCHEMBL3045729 | 0.69 | CNR2 (1.00) | CNR2CNR1MAPK1TSHRPKM | |
| SCHEMBL3042547 | 0.69 | CNR2 (1.00) | CNR2CNR1MAPK1 | |
| SCHEMBL3038878 | 0.69 | CNR2 (1.00) | CNR2CNR1MAPK1 | |
| SCHEMBL3158072 | 0.67 | CNR2 (0.95) | CNR2CNR1 | |
| SCHEMBL4866156 | 0.66 | TSHR (1.00) | MAPK1TSHRPKMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139852-A1 | SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS | Pharmos Corporation (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008075353-A1 | SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS | PHARMOS CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |