Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26103080 | 1.00 | TYK2 (0.43) | TYK2PDE4D | |
| SCHEMBL30392771 | 0.95 | TYK2 (0.43) | TYK2PDE4D | |
| SCHEMBL26098254 | 0.95 | TYK2 (0.43) | TYK2PDE4D | |
| SCHEMBL26098984 | 0.90 | TYK2 (0.41) | TYK2PDE4D | |
| SCHEMBL30392624 | 0.90 | TYK2 (0.41) | TYK2PDE4D | |
| SCHEMBL30392726 | 0.89 | TYK2 (0.40) | TYK2PDE4D | |
| SCHEMBL26102885 | 0.89 | TYK2 (0.40) | TYK2PDE4D | |
| SCHEMBL26099068 | 0.89 | TYK2 (0.44) | TYK2PDE4D | |
| SCHEMBL26101630 | 0.87 | TYK2 (0.47) | TYK2PDE4D | |
| SCHEMBL26101378 | 0.86 | TYK2 (0.61) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423086-A1 | TYK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |