Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812401 | 1.00 | TYK2 (0.83) | TYK2 | |
| SCHEMBL26101540 | 0.93 | TYK2 (0.82) | TYK2 | |
| SCHEMBL16812338 | 0.92 | TYK2 (0.80) | TYK2 | |
| SCHEMBL26101248 | 0.90 | TYK2 (0.81) | TYK2 | |
| SCHEMBL26100154 | 0.90 | TYK2 (0.81) | TYK2 | |
| SCHEMBL16812447 | 0.90 | TYK2 (0.76) | TYK2 | |
| SCHEMBL26101149 | 0.89 | TYK2 (0.82) | TYK2 | |
| SCHEMBL26101688 | 0.89 | TYK2 (0.79) | TYK2 | |
| SCHEMBL16812376 | 0.89 | TYK2 (1.00) | TYK2 | |
| SCHEMBL18143581 | 0.89 | TYK2 (1.00) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-4423086-A1 | TYK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |