Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 15/20 | 0.59 |
| ▸ | VSIR | Q9H7M9 | 12/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897882 | 1.00 | CD274 (0.59) | CD274PDCD1VSIR | |
| SCHEMBL19897881 | 1.00 | CD274 (0.59) | CD274PDCD1VSIR | |
| SCHEMBL29615156 | 0.92 | CD274 (0.52) | CD274PDCD1VSIR | |
| SCHEMBL19897517 | 0.92 | CD274 (0.52) | CD274PDCD1VSIR | |
| SCHEMBL19897516 | 0.92 | CD274 (0.52) | CD274PDCD1VSIR | |
| SCHEMBL19897912 | 0.90 | PDCD1 (0.60) | CD274PDCD1VSIR | |
| SCHEMBL30394805 | 0.90 | PDCD1 (0.60) | CD274PDCD1VSIR | |
| SCHEMBL19897915 | 0.90 | PDCD1 (0.60) | CD274PDCD1VSIR | |
| SCHEMBL19897693 | 0.86 | CD274 (0.54) | CD274PDCD1VSIR | |
| SCHEMBL19897696 | 0.86 | CD274 (0.54) | CD274PDCD1VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | claimed |
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |