Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897545 | 0.84 | KDM4E (0.44) | HTR1BLMNAHTR1DHTR7KDM4E | |
| SCHEMBL19897784 | 0.84 | HTR1B (0.42) | HTR1BLMNAHTR1DHRH1HTR7 | |
| SCHEMBL28960000 | 0.84 | HTR1B (0.46) | HTR1BLMNAMAPTKDM4EGAA | |
| SCHEMBL30668196 | 0.84 | HTR1B (0.46) | HTR1BLMNAMAPTKDM4EGAA | |
| SCHEMBL30394884 | 0.83 | HTR1B (0.45) | HTR1BLMNAMAPTKDM4EGAA | |
| SCHEMBL10681054 | 0.83 | HTR1B (0.45) | HTR1BLMNAMAPTKDM4EGAA | |
| SCHEMBL28469003 | 0.83 | HTR1B (0.45) | HTR1BLMNAMAPTKDM4EGAA | |
| SCHEMBL30786889 | 0.82 | HTR1B (0.47) | HTR1BHTR1DMAPTKDM4EGAA | |
| SCHEMBL30786892 | 0.82 | HTR1B (0.47) | HTR1BHTR1DMAPTKDM4EGAA | |
| SCHEMBL10678598 | 0.81 | HTR1B (0.45) | HTR1BLMNAHTR7MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |