Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323011 | 0.85 | GAA (0.44) | RHEBALDH1A1MEN1KMT2AFEN1 | |
| SCHEMBL24105185 | 0.82 | FEN1 (0.40) | RHEBMEN1KMT2AFEN1EIF4A3 | |
| SCHEMBL3959096 | 0.82 | EIF4A3 (0.53) | RHEBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL30310764 | 0.82 | EIF4A3 (0.53) | RHEBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL22394891 | 0.76 | IDO1 (0.65) | RHEBEIF4A3GRIN1DAOIDO1 | |
| SCHEMBL30396542 | 0.75 | HPGD (0.51) | RHEBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL27318461 | 0.75 | FEN1 (0.48) | RHEBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL24189547 | 0.75 | HPGD (0.51) | RHEBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29053569 | 0.73 | HSD17B10 (0.61) | RHEBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL20536074 | 0.73 | RHEB (0.62) | RHEBALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |