Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.66 |
| ▸ | PIK3R1 | P27986 | 10/20 | 0.66 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25397267 | 1.00 | PIK3CD (0.66) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL25397266 | 1.00 | PIK3CD (0.66) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL28572749 | 0.83 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061376 | 0.83 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL30396632 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL25396151 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL25396153 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL14726428 | 0.83 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL26246722 | 0.83 | PIK3CG (0.53) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL12688634 | 0.82 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115968369-A | Process for the preparation of compounds as PI3K inhibitors and intermediate compounds useful for the preparation thereof | 株式会社保宁 | 2023-04-14 | — | — | CN | disclosed |