SCHEMBL30397357

SCHEMBL30397357

COC(=O)C(=O)c1c(Cl)c(C(=O)Nc2ccc(F)c(F)c2)c2n1CCC2

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21378225 1.00 SLC10A1 (0.52) SLC10A1
SCHEMBL23223934 0.90 SLC10A1 (0.52) SLC10A1
SCHEMBL21296656 0.89 SLC10A1 (0.60) SLC10A1
SCHEMBL21296668 0.89 SLC10A1 (0.52) SLC10A1
SCHEMBL23223844 0.89 SLC10A1 (0.56) SLC10A1
SCHEMBL23224027 0.89 SLC10A1 (0.52) SLC10A1
SCHEMBL24571115 0.88 SLC10A1 (0.57) SLC10A1
SCHEMBL23223878 0.84 SLC10A1 (0.56) SLC10A1
SCHEMBL21810180 0.84 SLC10A1 (0.50) SLC10A1
SCHEMBL24570938 0.83 SLC10A1 (0.60) SLC10A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111788204-B Substituted pyrrolizine compounds as inhibitors of HBV replication 吉利德科学公司 2023-05-05 CN disclosed