Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25151296 | 1.00 | ERCC1 (0.34) | ERCC1ERCC4ATAD2TYMSDAO | |
| SCHEMBL27159808 | 0.84 | ERCC1 (0.37) | ERCC1ERCC4CHEK1 | |
| SCHEMBL25150856 | 0.81 | CHEK1 (0.35) | ERCC1ERCC4CHEK1 | |
| SCHEMBL25150835 | 0.80 | DPYD (0.36) | ERCC1ERCC4CHEK1 | |
| SCHEMBL27159963 | 0.80 | ERCC1 (0.35) | ERCC1ERCC4DAOCHEK1 | |
| SCHEMBL31714168 | 0.80 | DPYD (0.36) | ERCC1ERCC4CHEK1 | |
| SCHEMBL25151229 | 0.78 | PDE3B (0.40) | ERCC1ERCC4CHEK1 | |
| SCHEMBL27159759 | 0.76 | DAO (0.32) | ATAD2DAO | |
| SCHEMBL27157829 | 0.73 | TYMS (0.40) | TYMS | |
| SCHEMBL4574088 | 0.72 | PARP1 (0.45) | ATAD2TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416141-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | Remix Therapeutics Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| CN-117597336-A | Halogen substituted amino aza-heteroaryl compounds as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) | 安大略省癌症研究所(OICR) | 2024-02-23 | — | — | CN | disclosed |
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |