Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23004604 | 1.00 | MAOB (0.62) | MAOBMAOAFFAR1IDO1ACHE | |
| SCHEMBL257781 | 0.86 | MAOB (0.69) | MAOBMAOAFFAR1IDO1ACHE | |
| SCHEMBL15156233 | 0.85 | MAOB (0.73) | MAOBMAOAIDO1ACHE | |
| SCHEMBL30398600 | 0.83 | MAOB (0.66) | MAOBMAOAFFAR1IDO1ACHE | |
| SCHEMBL28498324 | 0.83 | MAOB (0.61) | MAOBMAOAFFAR1IDO1ACHE | |
| SCHEMBL14437517 | 0.83 | MAOB (0.66) | MAOBMAOAFFAR1IDO1ACHE | |
| SCHEMBL10866245 | 0.83 | MAOB (0.69) | MAOBMAOAFFAR1IDO1ACHE | |
| SCHEMBL21480345 | 0.83 | MAOB (0.78) | MAOBMAOAIDO1 | |
| SCHEMBL10204868 | 0.82 | MAOB (0.72) | MAOBMAOAFFAR1IDO1 | |
| SCHEMBL23004576 | 0.81 | MAOB (0.69) | MAOBMAOAFFAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240557-B | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业有限公司 | 2023-05-09 | — | — | CN | disclosed |