SCHEMBL30399372

SCHEMBL30399372

OCc1ccc(OCc2cccc(F)c2)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 18/20 0.60
MAOA P21397 6/20 0.60
NR4A2 P43354 2/20 0.53
PARP10 Q53GL7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23004618 1.00 MAOB (0.60) MAOBMAOANR4A2PARP10
SCHEMBL30398523 0.86 MAOB (0.60) MAOBMAOANR4A2PARP10
SCHEMBL23004581 0.86 MAOB (0.60) MAOBMAOANR4A2PARP10
SCHEMBL30398602 0.86 MAOB (0.61) MAOBMAOANR4A2PARP10
SCHEMBL23004608 0.86 MAOB (0.61) MAOBMAOANR4A2PARP10
SCHEMBL695003 0.84 S1PR1 (0.57) MAOBNR4A2
SCHEMBL23004589 0.83 MAOB (0.61) MAOBMAOANR4A2PARP10
SCHEMBL30398526 0.83 MAOB (0.61) MAOBMAOANR4A2PARP10
SCHEMBL157731 0.80 MAOB (0.66) MAOBMAOANR4A2PARP10
SCHEMBL29817726 0.79 MAOB (0.73) MAOBMAOANR4A2PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240557-B Pyrrolidine amide derivatives and use thereof 广东东阳光药业有限公司 2023-05-09 CN disclosed