Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416822 | 1.00 | ADORA2A (0.42) | ADORA2AADORA2BADORA1CPT2CPT1A | |
| SCHEMBL20401512 | 0.98 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL30401359 | 0.98 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL20401505 | 0.98 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL20416628 | 0.98 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL30401055 | 0.98 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL20436719 | 0.91 | ADORA2A (0.43) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL20416650 | 0.89 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL20417134 | 0.89 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 | |
| SCHEMBL26216935 | 0.89 | ADORA2A (0.42) | ADORA2AADORA2BADORA1SYKUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |