Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PAK4 | O96013 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666431 | 1.00 | PARP1 (0.56) | PARP1MAP2K1PIM1AURKADAPK3 | |
| SCHEMBL25433958 | 0.83 | PARP1 (0.61) | PARP1MAP2K1PIM1AURKADAPK3 | |
| SCHEMBL667427 | 0.81 | PARP1 (0.58) | PARP1MAP2K1PIM1AURKADAPK3 | |
| SCHEMBL2519442 | 0.80 | PARP1 (0.64) | PARP1MAP2K1PIM1AURKADAPK3 | |
| SCHEMBL536589 | 0.80 | PARP1 (0.64) | PARP1NR4A2CREBBP | |
| SCHEMBL30401648 | 0.79 | AXL (0.41) | PARP1MAP2K1PIM1AURKADAPK3 | |
| SCHEMBL24399568 | 0.79 | AXL (0.41) | PARP1MAP2K1PIM1AURKADAPK3 | |
| SCHEMBL24399628 | 0.78 | PARP1 (0.59) | PARP1MAP2K1PIM1RPS6KA3ALK | |
| SCHEMBL29393199 | 0.78 | MAP2K1 (0.65) | MAP2K1PSMD14NR4A2CREBBPKDM4E | |
| SCHEMBL24399553 | 0.77 | BCL2 (0.47) | PARP1MAP2K1ALKIP6K1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025228828-A1 | CARBOXAMIDE COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES | MERCK PATENT GMBH (DE) | 2025-11-06 | — | — | WO | disclosed |
| CN-117126140-A | Heterocyclic compounds having protein kinase inhibitory activity, pharmaceutical compositions containing the same, and methods of preparing and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |