Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 6/20 | 0.57 |
| ▸ | BRAF | P15056 | 6/20 | 0.57 |
| ▸ | AURKA | O14965 | 12/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 3/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.46 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399624 | 1.00 | RAF1 (0.57) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL25377008 | 0.97 | RAF1 (0.54) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL30402002 | 0.97 | RAF1 (0.54) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL30402340 | 0.95 | AURKA (0.53) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL24399756 | 0.95 | AURKA (0.53) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL25376182 | 0.95 | AURKA (0.54) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL30402711 | 0.95 | AURKA (0.54) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL25376850 | 0.93 | RAF1 (0.50) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL25375571 | 0.93 | AURKA (0.49) | RAF1BRAFAURKAAURKBRPS6KB1 | |
| SCHEMBL30401651 | 0.93 | AURKA (0.49) | RAF1BRAFAURKAAURKBRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |