Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 3/20 | 0.53 |
| ▸ | BRAF | P15056 | 3/20 | 0.53 |
| ▸ | CSF1R | P07333 | 2/20 | 0.53 |
| ▸ | ARAF | P10398 | 1/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.53 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25378433 | 1.00 | RAF1 (0.53) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL25374139 | 0.93 | RAF1 (0.56) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL30402492 | 0.93 | RAF1 (0.56) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL30401356 | 0.90 | RAF1 (0.55) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL24399613 | 0.90 | RAF1 (0.55) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL24399560 | 0.90 | RAF1 (0.55) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL30401716 | 0.90 | RAF1 (0.55) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL24399716 | 0.90 | RAF1 (0.55) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL30401297 | 0.90 | RAF1 (0.55) | RAF1BRAFCSF1RARAFDDR1 | |
| SCHEMBL24399732 | 0.89 | RAF1 (0.54) | RAF1BRAFCSF1RARAFDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |