Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 9/20 | 0.49 |
| ▸ | BRAF | P15056 | 9/20 | 0.49 |
| ▸ | CSF1R | P07333 | 5/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.43 |
| ▸ | ARAF | P10398 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 5/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375338 | 1.00 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399573 | 0.96 | RAF1 (0.54) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL30402843 | 0.96 | RAF1 (0.54) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL30402026 | 0.93 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399586 | 0.93 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL25376849 | 0.93 | RAF1 (0.48) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL30400485 | 0.91 | RAF1 (0.47) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399746 | 0.91 | RAF1 (0.47) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL25376097 | 0.90 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL30401718 | 0.90 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |