Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 13/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 7/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.47 |
| ▸ | RAF1 | P04049 | 5/20 | 0.45 |
| ▸ | BRAF | P15056 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.43 |
| ▸ | ARAF | P10398 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374976 | 1.00 | AURKA (0.49) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL30401863 | 0.95 | AURKA (0.49) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL30402488 | 0.95 | AURKA (0.49) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL24399693 | 0.95 | AURKA (0.49) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL24399606 | 0.95 | AURKA (0.49) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL25376015 | 0.93 | AURKA (0.48) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL25372766 | 0.93 | AURKA (0.48) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL24399562 | 0.93 | AURKA (0.48) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL25375423 | 0.93 | AURKA (0.48) | AURKARPS6KB1AURKBRAF1BRAF | |
| SCHEMBL30401799 | 0.93 | AURKA (0.48) | AURKARPS6KB1AURKBRAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |