Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401220 | 1.00 | ADORA2A (0.42) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL30402253 | 1.00 | ADORA2A (0.42) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20401215 | 1.00 | ADORA2A (0.42) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20416906 | 1.00 | ADORA2A (0.42) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20421967 | 0.96 | ADORA2A (0.41) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20416945 | 0.96 | ADORA2A (0.41) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20421934 | 0.96 | ADORA2A (0.41) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20416658 | 0.96 | ADORA2A (0.41) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20416800 | 0.96 | ADORA2A (0.41) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL20416955 | 0.96 | ADORA2A (0.41) | ADORA2AADORA2BADORA1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |