Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416900 | 1.00 | ADORA2A (0.42) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL30401961 | 0.91 | PDE4D (0.46) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL20416775 | 0.91 | PDE4D (0.46) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL30401568 | 0.88 | NOTUM (0.44) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL20416789 | 0.88 | NOTUM (0.44) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL30401203 | 0.88 | NOTUM (0.44) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL20416785 | 0.88 | NOTUM (0.44) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL20416790 | 0.88 | NOTUM (0.44) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL30402083 | 0.88 | NOTUM (0.44) | ADORA2AADORA2BADORA1PDE4DPDE4A | |
| SCHEMBL20416784 | 0.88 | ADORA2A (0.43) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |