Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 15/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401255 | 1.00 | ADORA2A (0.50) | ADORA2AADORA2BKDRTEKCYP19A1 | |
| SCHEMBL20436595 | 0.87 | ADORA2A (0.62) | ADORA2AADORA2BKDRCYP19A1 | |
| SCHEMBL20401354 | 0.85 | ADORA2A (0.52) | ADORA2AADORA2BKDRTEKCYP19A1 | |
| SCHEMBL30401330 | 0.85 | ADORA2A (0.52) | ADORA2AADORA2BKDRTEKCYP19A1 | |
| SCHEMBL20401295 | 0.85 | TEK (0.51) | ADORA2AADORA2BKDRTEKCYP19A1 | |
| SCHEMBL30402264 | 0.85 | TEK (0.51) | ADORA2AADORA2BKDRTEKCYP19A1 | |
| SCHEMBL20436596 | 0.83 | ADORA2A (0.54) | ADORA2AADORA2BCYP19A1 | |
| SCHEMBL20436604 | 0.83 | ADORA2A (0.51) | ADORA2AADORA2BCYP19A1 | |
| SCHEMBL20436589 | 0.83 | ADORA2A (0.51) | ADORA2AADORA2BCYP19A1 | |
| SCHEMBL20416780 | 0.83 | ADORA2A (0.49) | ADORA2AADORA2BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |