Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.47 |
| ▸ | LCK | P06239 | 6/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123032 | 0.95 | PTK6 (0.48) | PTK6LCKAURKBEGFRKDM4E | |
| SCHEMBL22123217 | 0.92 | PTK6 (0.48) | PTK6LCKAURKBEGFR | |
| SCHEMBL22124741 | 0.91 | PTK6 (0.40) | PTK6LCKAURKB | |
| SCHEMBL22123687 | 0.90 | PTK6 (0.48) | PTK6LCKAURKBEGFRHTR2A | |
| SCHEMBL32675695 | 0.89 | PTK6 (0.42) | PTK6LCKAURKBBRD4BRDT | |
| SCHEMBL25452721 | 0.89 | PTK6 (0.40) | PTK6LCKAURKB | |
| SCHEMBL24112493 | 0.89 | PTK6 (0.41) | PTK6LCKAURKBEGFR | |
| SCHEMBL30172007 | 0.89 | PTK6 (0.38) | PTK6EGFRSMN1; SMN2 | |
| SCHEMBL22124671 | 0.89 | PTK6 (0.38) | PTK6EGFRSMN1; SMN2 | |
| SCHEMBL25450748 | 0.86 | PTK6 (0.39) | PTK6LCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | claimed |