SCHEMBL30402885

SCHEMBL30402885

CN(C)Cc1c(-c2ccc(N)cc2)sc2c1c(=O)n(-c1ccc(OC3COC3)nn1)c(=O)n2Cc1c(F)cccc1F

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.65
KCNH2 Q12809 12/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24333938 0.92 GNRHR (0.67) GNRHRKCNH2
SCHEMBL29519173 0.91 GNRHR (0.56) GNRHRKCNH2
SCHEMBL30402722 0.91 GNRHR (0.66) GNRHRKCNH2
SCHEMBL30401433 0.90 GNRHR (0.65) GNRHRKCNH2
SCHEMBL29384672 0.89 GNRHR (0.80) GNRHRKCNH2
SCHEMBL15639971 0.89 GNRHR (0.80) GNRHRKCNH2
SCHEMBL24333937 0.89 GNRHR (0.84) GNRHRKCNH2
SCHEMBL29519101 0.89 GNRHR (0.55) GNRHRKCNH2
Hydrochloric Acid SCHEMBL30174360 0.88 GNRHR (0.79) GNRHRKCNH2
SCHEMBL29519041 0.88 GNRHR (0.64) GNRHRKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096371-A Pyrimidine diketone compound containing saturated oxygen heterocyclic group and application thereof 广东东阳光药业有限公司 2023-05-09 CN disclosed