Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.58 |
| ▸ | TYK2 | P29597 | 6/20 | 0.51 |
| ▸ | JAK2 | O60674 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | JAK1 | P23458 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30402844 | 0.88 | ANO1 (0.61) | ANO1TYK2JAK2JAK1RECQL | |
| SCHEMBL29029227 | 0.88 | ANO1 (0.58) | ANO1TYK2JAK2SMN1; SMN2JAK1 | |
| SCHEMBL30368167 | 0.81 | TYK2 (0.67) | ANO1TYK2JAK2SMN1; SMN2JAK1 | |
| SCHEMBL30368101 | 0.78 | SMN1; SMN2 (0.65) | ANO1TYK2JAK2SMN1; SMN2JAK1 | |
| SCHEMBL30368260 | 0.77 | ANO1 (0.53) | ANO1TYK2JAK2JAK1RECQL | |
| SCHEMBL29029218 | 0.76 | ANO1 (0.55) | ANO1SMN1; SMN2P2RX4RECQLTSHR | |
| SCHEMBL30368230 | 0.75 | JAK2 (0.62) | ANO1TYK2JAK2JAK1P2RX4 | |
| SCHEMBL26186541 | 0.75 | P2RX4 (0.74) | ANO1SMN1; SMN2P2RX4RECQLTSHR | |
| SCHEMBL30285760 | 0.75 | P2RX4 (0.74) | ANO1SMN1; SMN2P2RX4RECQLTSHR | |
| SCHEMBL21198322 | 0.74 | ANO1 (1.00) | ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |