Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044311 | 0.91 | LPAR1 (0.48) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3039799 | 0.89 | LPAR1 (0.44) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3049046 | 0.89 | LPAR1 (0.46) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3051293 | 0.88 | LPAR1 (0.46) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3039747 | 0.88 | LPAR1 (0.42) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL2332531 | 0.86 | LPAR1 (0.52) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3714441 | 0.85 | LPAR1 (0.54) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL25236847 | 0.84 | LPAR1 (0.49) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3706535 | 0.84 | LPAR1 (0.53) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL2335320 | 0.84 | LPAR1 (0.53) | LPAR1LPAR3LPAR2SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068775-A2 | ALKYNE ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | WO | disclosed |