Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110590 | 1.00 | HTR2C (0.42) | HTR2CHTR6POLBL3MBTL1HTR2A | |
| SCHEMBL24110627 | 1.00 | HTR2C (0.42) | HTR2CHTR6POLBL3MBTL1HTR2A | |
| SCHEMBL24109843 | 1.00 | HTR2C (0.42) | HTR2CHTR6POLBL3MBTL1HTR2A | |
| SCHEMBL24109861 | 0.89 | HTR2A (0.47) | HTR2CHTR6HTR2ATFPI2ROCK1 | |
| SCHEMBL24110281 | 0.85 | TFPI2 (0.42) | HTR2CHTR2ATFPI2MEN1ALDH1A1 | |
| SCHEMBL24110321 | 0.83 | FFAR4 (0.38) | ROCK1 | |
| SCHEMBL24109771 | 0.82 | TFPI2 (0.37) | TFPI2 | |
| SCHEMBL24109875 | 0.81 | HTR2A (0.37) | HTR2CHTR2ATFPI2ROCK1FABP4 | |
| SCHEMBL24109711 | 0.81 | HTR2C (0.42) | HTR2CHTR6POLBL3MBTL1HTR2A | |
| SCHEMBL25820772 | 0.81 | HTR2C (0.42) | HTR2CHTR6POLBL3MBTL1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165049-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | Delix Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |