Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301751 | 1.00 | HTR2C (0.43) | HTR2CHTR2AUSP2ALDH1A1CYP1A2 | |
| SCHEMBL24110220 | 1.00 | HTR2C (0.43) | HTR2CHTR2AUSP2ALDH1A1CYP1A2 | |
| SCHEMBL24110210 | 0.84 | HTR2C (0.62) | HTR2CHTR2A | |
| SCHEMBL25296103 | 0.84 | HTR2C (0.62) | HTR2CHTR2A | |
| SCHEMBL25818036 | 0.82 | HTR2A (0.38) | HTR2CHTR2ACYP1A2GLO1 | |
| SCHEMBL30404903 | 0.82 | HTR2C (0.43) | HTR2CHTR2AKDM4EMEN1MAPT | |
| SCHEMBL24110211 | 0.82 | HTR2C (0.43) | HTR2CHTR2AKDM4EMEN1MAPT | |
| SCHEMBL25300885 | 0.82 | HTR2C (0.43) | HTR2CHTR2AKDM4EMEN1MAPT | |
| SCHEMBL24109831 | 0.78 | HTR2C (0.57) | HTR2CHTR2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL30403505 | 0.78 | HTR2C (0.57) | HTR2CHTR2AALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165049-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | Delix Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |