Bromide

Bromide

SCHEMBL3040545

CCCCCC[n+]1ccc(N2CCC(C)CC2)cc1.[Br-]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.45
CHRM4 known ✓ P08173 1/20 0.45
CHRM5 known ✓ P08912 1/20 0.45
CHRM1 known ✓ P11229 1/20 0.45
CHRM3 known ✓ P20309 1/20 0.45
ACHE known ✓ P22303 1/20 0.45
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
MAPT P10636 2/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
HTT P42858 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3040650 0.98 MEN1 (0.50) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL15923364 0.83 CHKA (0.56) ACHE
Hydrochloric Acid SCHEMBL261263 0.80 SMN1; SMN2 (0.38) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL9833857 0.77 SMN1; SMN2 (0.38) SMN1; SMN2NPC1RAB9AACHE
Bromide SCHEMBL15923659 0.77 CHKA (0.45) ACHE
Hydrochloric Acid SCHEMBL9676684 0.76 SMN1; SMN2 (0.37) SMN1; SMN2NPC1RAB9AACHE
Hydrochloric Acid SCHEMBL9172857 0.76 SMN1; SMN2 (0.37) KMT2AMEN1MAPTSMN1; SMN2KDM4E
SCHEMBL15211999 0.76 CHKA (0.56) ACHE
Hydrochloric Acid SCHEMBL8959777 0.75 GAA (0.40) KMT2AMEN1MAPTSMN1; SMN2LMNA
Iodide SCHEMBL15212172 0.74 CHKA (0.54) HTTSMN1; SMN2LMNAKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516236-B1 Method of oil recovery from subsurface reservoirs using improved carbon dioxide enhanced oil recovery KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-06 US disclosed
US-9550936-B2 Mobilization of heavy oil BAKER HUGHES INCORPORATED (US) 2017-01-24 US disclosed
US-20140045732-A1 MOBILIZATION OF HEAVY OIL BAKER HUGHES INCORPORATED (US) 2014-02-13 US disclosed
US-8211283-B2 Microfabricated liquid junction reference electrode TELEDYNE SCIENTIFIC & IMAGING, LLC (US) 2012-07-03 US disclosed
US-20110056831-A1 MICROFABRICATED LIQUID JUNCTION REFERENCE ELECTRODE TELEDYNE SCIENTIFIC & IMAGING, LLC (US) 2011-03-10 US disclosed
US-7687513-B1 Aminopyridinium ionic liquids UNIVERSITY OF NOTRE DAME DU LAC (US) 2010-03-30 US disclosed