Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415753 | 1.00 | CDC7 (0.51) | CDC7CDK2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL1150333 | 0.85 | CDC7 (0.54) | CDC7CDK2KDM4EPARP1CYP2C19 | |
| SCHEMBL30828406 | 0.85 | CDC7 (0.54) | CDC7CDK2KDM4EPARP1CYP2C19 | |
| SCHEMBL14223974 | 0.84 | MAPKAPK2 (0.45) | CDC7CDK2CYP2A6CYP3A4KDM4E | |
| SCHEMBL2294384 | 0.84 | CDC7 (0.53) | CDC7CDK2KDM4EMKNK2PARP1 | |
| SCHEMBL2295440 | 0.83 | CDC7 (0.56) | CDC7CDK2KDM4EMKNK2PARP1 | |
| Hydrochloric Acid SCHEMBL30335602 | 0.82 | CDC7 (0.51) | CDC7CDK2PTK2KDM4EMKNK2 | |
| SCHEMBL4804886 | 0.81 | CDC7 (0.42) | CDC7CDK2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL2295195 | 0.80 | CDC7 (0.53) | CDC7CDK2KDM4EMKNK2PARP1 | |
| SCHEMBL4859211 | 0.80 | MAPT (0.42) | CDC7CDK2CYP2A6CYP3A4CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |