Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TAF1 | P21675 | 1/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924982 | 1.00 | ERN1 (0.48) | ERN1HPGDALDH1A1PKMPHGDH | |
| SCHEMBL14925050 | 0.88 | ERN1 (0.48) | ERN1ALDH1A1CHEK1BRD4TAF1 | |
| SCHEMBL14924921 | 0.87 | ERN1 (0.51) | ERN1ALDH1A1KMT2A | |
| SCHEMBL14924896 | 0.85 | ERN1 (0.59) | ERN1ALDH1A1CHEK1 | |
| SCHEMBL14930180 | 0.83 | HPGD (0.40) | ERN1HPGDALDH1A1KMT2A | |
| SCHEMBL2551435 | 0.83 | TNKS2 (0.50) | ERN1HPGDALDH1A1KMT2A | |
| SCHEMBL14925297 | 0.81 | HPGD (0.49) | ERN1HPGDALDH1A1PKMPHGDH | |
| SCHEMBL14925035 | 0.78 | ERN1 (0.47) | ERN1HPGDALDH1A1 | |
| SCHEMBL14924908 | 0.77 | ERN1 (0.48) | ERN1 | |
| SCHEMBL14924898 | 0.76 | ERN1 (0.63) | ERN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172051-B | IRE-1 alpha inhibitors | 复星弘创(苏州)医药科技有限公司 | 2023-03-07 | — | — | CN | disclosed |