Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25198845 | 1.00 | DYRK1A (0.39) | DYRK1ACLK1CLK2CLK3CYP2A6 | |
| SCHEMBL30348808 | 0.87 | CYP2A6 (0.43) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL25158074 | 0.87 | CYP2A6 (0.43) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL30347008 | 0.84 | CYP2A6 (0.41) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL25158444 | 0.84 | CYP2A6 (0.38) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL30348957 | 0.84 | CYP2A6 (0.38) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL25158576 | 0.84 | CYP2A6 (0.41) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL30347799 | 0.82 | CDK2 (0.46) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL25212290 | 0.82 | CDK2 (0.46) | DYRK1ACLK1CYP2A6CDK2CCNT1 | |
| SCHEMBL25158234 | 0.82 | CYP2A6 (0.39) | DYRK1ACLK1CYP2A6CDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | DYRK1A 1/4885CLK1 355/4885CLK2 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.