Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932407 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27955705 | 0.96 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27985155 | 0.85 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL29781093 | 0.81 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2775308 | 0.77 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3284080 | 0.77 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL28301715 | 0.77 | CYP3A4 (0.31) | ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28285195 | 0.76 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Butane SCHEMBL1325593 | 0.76 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| Trimethylammonium SCHEMBL27893212 | 0.75 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027791-A | Weather-resistant gel coat type composite material with easily-identified characteristics | 河北多凯复合材料有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116731582-B | Acrylic resin fluorescent luminous paint and preparation method thereof | 南通市乐佳涂料有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-115746202-B | Water treatment agent and preparation method thereof | 滁州康华电子材料有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116731582-A | Acrylic resin fluorescent luminous paint and preparation method thereof | 南通市乐佳涂料有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115746202-A | Water treatment agent and preparation method thereof | 滁州康华电子材料有限公司 | 2023-03-07 | — | — | CN | disclosed |