SCHEMBL30407180

SCHEMBL30407180

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCC[C@H](N)C(=O)N[C@@H](C)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.39
▸ MAPT P10636 1/20 0.39
▸ NPSR1 Q6W5P4 3/20 0.38
▸ GLP1R P43220 8/20 0.35
▸ ATM Q13315 2/20 0.34
▸ DPP7 Q9UHL4 1/20 0.34
▸ POLB P06746 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ GNAI3 P08754 1/20 0.33
▸ GNAO1 P09471 1/20 0.33
▸ GNAI1 P63096 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ BIRC2 Q13490 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30407618 0.98 TDP1 (0.38) TDP1MAPTNPSR1GLP1RATM
SCHEMBL30407749 0.98 TDP1 (0.38) TDP1MAPTNPSR1GLP1RATM
SCHEMBL30408069 0.90 MAPT (0.36) TDP1MAPTGLP1RATMDPP7
SCHEMBL30407214 0.88 MEN1 (0.35) TDP1MAPTNPSR1GLP1RATM
SCHEMBL17833155 0.83 GLP1R (0.44) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL17833042 0.83 GLP1R (0.48) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL19707982 0.83 GLP1R (0.40) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL23451329 0.82 DPP7 (0.40) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL23451330 0.82 DPP7 (0.40) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL29467697 0.82 DPP7 (0.40) GLP1RDPP7GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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