SCHEMBL30407599

SCHEMBL30407599

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCC[C@H](NC(=O)CCCN1C(=O)C=CC1=O)C(=O)NCCCC(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.50
▸ HPGD P15428 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ GLO1 Q04760 1/20 0.34
▸ DGAT1 O75907 4/20 0.33
▸ SIRT2 Q8IXJ6 2/20 0.33
▸ CCKAR P32238 2/20 0.33
▸ CCKBR P32239 2/20 0.33
▸ ROCK2 O75116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30407169 1.00 GLP1R (0.50) GLP1RHPGDHTTSMN1; SMN2GLO1
SCHEMBL25682843 0.99 GLP1R (0.49) GLP1RHPGDHTTSMN1; SMN2GLO1
SCHEMBL29467677 0.94 GLP1R (0.47) GLP1RDGAT1CCKARCCKBR
SCHEMBL23451314 0.93 GLP1R (0.51) GLP1RHPGDHTTSMN1; SMN2DGAT1
SCHEMBL23451315 0.93 GLP1R (0.51) GLP1RHPGDHTTSMN1; SMN2DGAT1
SCHEMBL29467662 0.93 GLP1R (0.51) GLP1RHPGDHTTSMN1; SMN2DGAT1
SCHEMBL25683102 0.92 GLP1R (0.50) GLP1RHPGDHTTSMN1; SMN2DGAT1
SCHEMBL30407109 0.91 GLP1R (0.51) GLP1RGLO1SIRT2CCKARCCKBR
SCHEMBL29467601 0.90 GLP1R (0.49) GLP1RGLO1SIRT2CCKARCCKBR
SCHEMBL30407756 0.90 GLP1R (0.49) GLP1RGLO1SIRT2CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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