SCHEMBL30408279

SCHEMBL30408279

CSCC[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CCCCNC(C)=O)C(=O)O)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 17/20 0.48
▸ FNTB P49356 17/20 0.48
▸ PGGT1B P53609 10/20 0.48
▸ FOLH1 Q04609 2/20 0.46
▸ SIRT5 Q9NXA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29525963 0.86 FNTA (0.50) FNTAFNTBPGGT1BFOLH1
SCHEMBL31067326 0.86 FNTA (0.50) FNTAFNTBPGGT1BFOLH1
SCHEMBL30051582 0.86 FNTA (0.58) FNTAFNTBPGGT1B
SCHEMBL34473997 0.86 FNTA (0.58) FNTAFNTBPGGT1B
SCHEMBL20844324 0.85 FOLH1 (0.56) FNTAFNTBPGGT1BFOLH1
SCHEMBL31688029 0.84 FNTA (0.51) FNTAFNTBPGGT1B
SCHEMBL30495535 0.84 FNTA (0.51) FNTAFNTBPGGT1BFOLH1
SCHEMBL25712593 0.84 FNTA (0.45) FNTAFNTBPGGT1B
SCHEMBL30408473 0.83 FNTA (0.48) FNTAFNTBPGGT1BFOLH1
SCHEMBL31643025 0.82 FNTA (0.49) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104794-A1 LINKER TECHNOLOGY FOR REDUCED RENAL RETENTION PAUL SCHERRER INSTITUT (CH) 2023-06-15 — — WO disclosed
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