Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24216211 | 1.00 | HDAC6 (0.49) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL25350996 | 0.94 | HDAC6 (0.49) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL30410398 | 0.94 | HDAC6 (0.49) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL30409392 | 0.94 | HDAC6 (0.49) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL24216698 | 0.94 | HDAC6 (0.49) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL25350716 | 0.92 | HDAC6 (0.47) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL25352280 | 0.91 | HDAC6 (0.46) | HDAC6KDM4EUCHL5KDRTEK | |
| SCHEMBL30424695 | 0.90 | HDAC6 (0.51) | HDAC6UCHL5KDRTEKHDAC1 | |
| SCHEMBL25216547 | 0.90 | HDAC6 (0.51) | HDAC6UCHL5KDRTEKHDAC1 | |
| SCHEMBL30410460 | 0.90 | HDAC6 (0.47) | HDAC6KDM4EUCHL5KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |