Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.43 |
| ▸ | TEK | Q02763 | 6/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407973 | 0.87 | HDAC6 (0.51) | HDAC6HDAC1 | |
| SCHEMBL30409501 | 0.83 | HDAC6 (0.55) | HDAC6EPHB4TEKKDRMEN1 | |
| SCHEMBL25349857 | 0.83 | HDAC6 (0.51) | HDAC6EPHB4TEKKDR | |
| SCHEMBL25349528 | 0.83 | HDAC6 (0.51) | HDAC6EPHB4TEKKDR | |
| SCHEMBL25352264 | 0.82 | HDAC6 (0.53) | HDAC6EPHB4TEKKDR | |
| SCHEMBL25213319 | 0.80 | HDAC6 (0.56) | HDAC6EPHB4TEKKDRMEN1 | |
| SCHEMBL30409448 | 0.80 | HDAC6 (0.49) | HDAC6EPHB4TEKKDRHDAC1 | |
| SCHEMBL25350732 | 0.80 | HDAC6 (0.49) | HDAC6EPHB4TEKKDRHDAC1 | |
| SCHEMBL25217353 | 0.80 | HDAC6 (0.52) | HDAC6EPHB4TEKKDRMEN1 | |
| SCHEMBL30425888 | 0.80 | HDAC6 (0.52) | HDAC6EPHB4TEKKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |